Review | |||||
Dementia and Neurocognitive Disorders 2015: 14: 1: 1-11 | |||||
Late-Onset Psychosis; Is It Real? | |||||
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Yong Tae Kwak,1 YoungSoon Yang,2 Min-Seong Koo3 | |||||
1Department of Neurology, Hyoja Geriatric Hospital, Yongin, Korea 2Department of Neurology, VHS Medical Center, Seoul, Korea 3Department of Psychiatry, College of Medicine, Kwandong University, Gangneung, Korea | |||||
Late-Onset Psychosis; Is It Real? | |||||
Yong Tae Kwak,1 YoungSoon Yang,2 Min-Seong Koo3 | |||||
1Department of Neurology, Hyoja Geriatric Hospital, Yongin, Korea 2Department of Neurology, VHS Medical Center, Seoul, Korea 3Department of Psychiatry, College of Medicine, Kwandong University, Gangneung, Korea | |||||
The nature of late-onset psychosis in the absence of a dementia or secondary to organic dysfunctions in the fifth decade of life and beyond is contentious and unresolved. Different terminologies, diagnostic criteria and age cut-offs have been applied to late-onset psychosis, which have stymied clinicians and researchers. No official diagnostic designation for patients with late-onset psychosis is included in the current psychiatric diagnostic system (Diagnostic and Statistical Manual of Mental Disorders-V, International Classification of Diseases-10). The validity of this diagnostic exclusion has been questioned. Despite these problems, a relatively consistent clinical picture has reported. However, many questions remain regarding the underlying etiology, pathophysiological mechanisms, treatment and prognosis. Whether late-onset psychosis is distinct from schizophrenia and whether it might be a harbinger of dementia are unclear. Recent studies have suggested an underlying biological pathophysiology of late-onset psychosis. Key Words late-onset psychosis, dementia, nosocology, schizophrenia. |
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Key Words: late-onset psychosis, dementia, nosocology, schizophrenia. | |||||
대한치매학회지 (Dementia and Neurocognitive Disorders) |