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Review
Dementia and Neurocognitive Disorders 2015: 14: 1: 1-11

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Late-Onset Psychosis; Is It Real?
Yong Tae Kwak,1 YoungSoon Yang,2 Min-Seong Koo3
1Department of Neurology, Hyoja Geriatric Hospital, Yongin, Korea 2Department of Neurology, VHS Medical Center, Seoul, Korea 3Department of Psychiatry, College of Medicine, Kwandong University, Gangneung, Korea
Late-Onset Psychosis; Is It Real?
Yong Tae Kwak,1 YoungSoon Yang,2 Min-Seong Koo3
1Department of Neurology, Hyoja Geriatric Hospital, Yongin, Korea 2Department of Neurology, VHS Medical Center, Seoul, Korea 3Department of Psychiatry, College of Medicine, Kwandong University, Gangneung, Korea
The nature of late-onset psychosis in the absence of a dementia or secondary to organic dysfunctions in the fifth decade of life and beyond is contentious and unresolved. Different terminologies, diagnostic criteria and age cut-offs have been applied to late-onset psychosis, which have stymied clinicians and researchers. No official diagnostic designation for patients with late-onset psychosis is included in the current psychiatric diagnostic system (Diagnostic and Statistical Manual of Mental Disorders-V, International Classification of Diseases-10). The validity of this diagnostic exclusion has been questioned. Despite these problems, a relatively consistent clinical picture has reported. However, many questions remain regarding the underlying etiology, pathophysiological mechanisms, treatment and prognosis. Whether late-onset psychosis is distinct from schizophrenia and whether it might be a harbinger of dementia are unclear. Recent studies have suggested an underlying biological pathophysiology of late-onset psychosis.
Key Words late-onset psychosis, dementia, nosocology, schizophrenia.
Key Words: late-onset psychosis, dementia, nosocology, schizophrenia.
대한치매학회지 (Dementia and Neurocognitive Disorders)