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Original Article
Dementia and Neurocognitive Disorders 2008: 7: 1: 1-9

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노인 치매 환자의 행동심리 증상과 부양부담과의 관계
유봉구∙김응규*∙김재우†∙김태유‡∙박경원†∙성상민§∙윤수진‖∙윤성민¶∙이상찬**∙최문성††∙홍태용‡∙김수영§§
고신대학교 의과대학 신경과
인제대학교 부산백병원 신경과*
동아대학교 의과대학 신경과†
윌리스병원 신경과‡, 부산의료원 신경과§
을지대학교 의과대학 신경과학교실‖
삼일정풍병원 신경과¶, 동의의료원 신경과**
메리놀병원 신경과††, 김해한솔병원 신경과††
경성대학교 사회복지학과§§
Relationship between Behavioral and Psychological Symptoms of Dementia and Caregiver Burden
Bong Goo Yoo, M.D., Eung Gyu Kim, M.D.*, Jae Woo Kim, M.D.†, Tae You Kim, M.D.‡, Kyung Won Park, M.D.†, Sang Min Sung, M.D.§, Soo Jin Yoon, M.D.‖, Sung Min Yoon, M.D.¶, Sang Chan Lee, M.D.**, Mun Seong Choi, M.D.††, Tae Yong Hong, M.D.‡, Soo Young Kim, Ph.D.§§
Department of Neurology, Kosin University College of Medicine, Busan;
Department of Neurology*, Inje University College of Medicine, Busan;
Department of Neurology†, Dong-A University College of Medicine, Busan;
Department of Neurology‡, Willis Hospital, Busan;
Department of Neurology§, Busan Medical Center, Busan;
Department of Neurology‖, Eulgi University School of Medicine, Daejeon;
Department of Neurology¶, Samil Jeongpoong Hospital, Masan;
Department of Neurology**, Dongeui Medical Center, Busan;
Department of Neurology††, Maryknoll Hospital, Busan;
Department of Neurology††, Gimhae Hansol Hospital, Gimhae;
Department of Social Welfare§§, Kyungsung University, Busan, Korea
Background: Behavioral and psychological symptoms of dementia (BPSD) are a source of distress and burden for caregivers. This study was designed to determine the relationship between BPSD and their impact on caregivers. Methods: The subjects were 144 participants with dementia living with their caregivers. There were 98 Alzheimer’s disease (AD) patients and 46 vascular dementia (VaD) patients. Burden Interviews and the Caregiver Burden Inventory, the Korean version of the Neuropsychiatric Inventory (K-NPI), were conducted by face-to-face interviews with the caregivers. Results: Approximately seventy percent of the caregivers were women, and their mean age was 54-yr-old. Forty-two percent of the caregivers were spouses. Among the individuals with dementia, apathy/indifference, depression, agitation/aggression, irritability/lability and anxiety were found in the highest frequencies. Caregiver burden was associated with apathy/indifference, disinhibition, irritability/lability, anxiety, and appetite/eating disorders in the K-NPI. There were significant correlations of K-NPI subscale scores of agitation, anxiety, apathy/indifference, irritability/lability, disinhibition, aberrant motor behavior, and appetite/eating disorders with caregiver burden. Multiple regression analysis revealed that disinhibition and irritability/lability were independently associated with caregiver burden. Conclusions: Our study demonstratedthat caregiver burden is affected more by the demented patient’s BPSD than conditions due to their decreased cognitive functions. These findings suggest that some symptoms such as disinhibition, and irritability/lability may affect the caregiver burden significantly.
Key Words: Behavioral and psychological symptoms of dementia (BPSD), Caregiver burden, Dementia, Korean version of neuropsychiatric inventory (K-NPI)

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