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| Review | |||||
| Dementia and Neurocognitive Disorders 2023: 22: 1: 16-27 | |||||
| Diagnostic Tools for Alzheimer’s Disease: A Narrative Review Based on Our Own Research Experience | |||||
|---|---|---|---|---|---|
| So-Hee Park , 1 Kyoung Ja Kwon , 2 Min Young Kim , 3 Jae-Hun Kim , 4 Won-Jin Moon , 5 Hui Jin Ryu , 3 Jae Won Jang , 6 Yeonsil Moon , 3 K-ARPI | |||||
| 1 Department of Neurology, Bobath Memorial Hospital, Seongnam, Korea 2 Center for Geriatric Neuroscience Research, Institute of Biomedical Science and Technology, Konkuk University School of Medicine, Seoul, Korea 3 Department of Neurology, Konkuk University School of Medicine, Seoul, Korea 4 Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea 5 Department of Radiology, Konkuk University School of Medicine, Seoul, Korea 6 Department of Neurology, Kangwon National University Hospital, Kangwon National University, Chuncheon, Korea | |||||
| Diagnostic Tools for Alzheimer’s Disease: A Narrative Review Based on Our Own Research Experience | |||||
| So-Hee Park , 1 Kyoung Ja Kwon , 2 Min Young Kim , 3 Jae-Hun Kim , 4 Won-Jin Moon , 5 Hui Jin Ryu , 3 Jae Won Jang , 6 Yeonsil Moon , 3 K-ARPI | |||||
| 1 Department of Neurology, Bobath Memorial Hospital, Seongnam, Korea 2 Center for Geriatric Neuroscience Research, Institute of Biomedical Science and Technology, Konkuk University School of Medicine, Seoul, Korea 3 Department of Neurology, Konkuk University School of Medicine, Seoul, Korea 4 Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea 5 Department of Radiology, Konkuk University School of Medicine, Seoul, Korea 6 Department of Neurology, Kangwon National University Hospital, Kangwon National University, Chuncheon, Korea | |||||
| Alzheimer’s disease (AD), one of the most representative neurodegenerative diseases, has diverse neurobiological and pathophysiological mechanisms. Treatment strategies targeting a single mechanism have repeated faced failures because the mechanism of neuronal cell death is very complex that is not fully understood yet. Since complex mechanisms exist to explain AD, a variety of diagnostic biomarkers for diagnosing AD are required. Moreover, standardized evaluations for comprehensive diagnosis using neuropsychological, imaging, and laboratory tools are needed. In this review, we summarize the latest clinical, neuropsychological, imaging, and laboratory evaluations to diagnose patients with AD based on our own experience in conducting a prospective study. |
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| Key Words: Dementia; Biomarkers; Diagnosis | |||||
| 대한치매학회지 (Dementia and Neurocognitive Disorders) | |||||
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