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Original Article
Dementia and Neurocognitive Disorders 2003: 2: 1: 23-28

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알쯔하이머 환자의 인지-임상 정도 평가 척도
김태유, 양동원*, 김상윤†, 김재우‡, 임병훈§
부산동인노인병원 신경과, 가톨릭대학교 신경과학교실*, 서울대학교 신경과학교실†, 동아대학교 신경과학교실‡, 경상대학교 신경과학교실§
Cognitive-Clinical Dementia Rating Scale for Alzheimer's Disease Patient
Tae-You Kim, M.D., Dong-Won Yang, M.D.*, Sang Yun Kim, M.D.†, Jae Woo Kim, M.D.‡, and Byeong Hoon Lim, M.D.§
Department of Neurology, Seoul National University College of Medicine†, Seoul; Department of Neurology, Dong-A University College of Medicine‡, Busan; Department of Neurology, Gyeongsang National University College of Medicine§, Jinju, Korea
Background : There are many global assessment scales for Alzheimer's disease. The Clinical Dementia Rating Scale (CDR), the Global Deterioration Scale (GDS) and the Blessed Dementia Rating scale have been widely used for evaluating the severity of dementia and might be useful for measuring the change of a patient's status. The CDR has been regarded as the golden standard for the severity of dementia. However, this interview-based scale takes up to 30 min for the clinician to complete, which is impractical in many clinical settings. Furthermore it is not so much sensitive for detecting the change of disease progression in each cognitive domain. We developed a brief and reliable questionnaire for evaluating the severity of dementia, called Cognitive-Clinical Dementia Rating Scale (CCDR). Methods : The CCDR consists of 15 questions that allow to assess the orientation to time, the orientation to place, the orientation to person, memory, attention, language, visuospatial function, frontal executive function, physical self maintenance, home and hobbies, community affair, the duration of dementia, mental alertness, walking ability, onset of abnormal behavior and character change. Ninety-eight probable and possible AD patients received the Clinical Dementia Rating Scale (CDR), Korean version of Mini-Mental State Examination (K-MMSE) and Cognitive-Clinical Dementia Rating Scale (CCDR). We tested validity and reliability. Results : The CCDR was significantly correlated with CDR (r=0.86, p<0.01) and K-MMSE (r=-0.88, p<0.01) and internal consistency was 0.96. Conclusion : The CCDR may be an easy and brief rating scale for the global assessment of Alzheimer's disease with excellent validity and reliability.
Key Words: Alzheimer's disease, Dementia, Global scale, Assessment