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Case Report
Dementia and Neurocognitive Disorders 2014: 13: 4: 146-149

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반복적 이상행동과 기억저하를 주증상으로 나타낸 인슐린종
손상욱*·윤별아*·이형진* 심동현*·박경원*,†
동아대학교 의과대학 신경과학교실* 동아대학교병원 인지장애 치매센터
A Case of Insulinoma Presenting as Repetitive Abnormal Behavior with Amnesia
Sang Wuk Sohn, M.D.*, Byeol A Yoon, M.D.*, Hyung Jin Lee, M.D.*, Dong-Hyun Shim, M.D.*, Kyung Won Park, M.D.*,†
Department of Neurology*, Dong-A University College of Medicine, Busan; Cognitive Disorders and Dementia Center†, Dong-A University Hospital, Busan, Korea
Insulinomas are very rare tumors. Diagnosis of insulinoma is often delayed or misdiagnosed because of its various symptoms. We report a patient with hypoglycemic encephalopathy who had repetitive behavior changes, diagnosed as a pancreatic insulinoma. A 52 years old man was referred to a memory and dementia clinic for evaluation of his repetitive abnormal behavior changes. He has threatened his wife with violent acts and showed aggressive behaviors, but he couldn’t remember when he was recovered to normal state. During the hospitalization, we noticed that his repetitive abnormal behaviors were correlated to severe hypoglycemia. After we corrected glucose level, his symptoms were disappeared. We performed an abdomen-pelvis CT scan, revealing pancreatic head tumor. After he took surgical treatment, His symptoms were fully recovered. Our case demonstrates that various neurological symptoms, such as abnormal behavior, rarely occur due to recurrent hypoglycemia in patient with insulinoma.
Key Words: Insulinoma, Hypoglycemic encephalopathy, Neuropsychiatric symptoms
대한치매학회지 (Dementia and Neurocognitive Disorders)