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단락수술 후 전두엽성 인지장애의 현저한 호전을 보인 특발성 정상압수두증 1예
Case Report
Dementia and Neurocognitive Disorders 2002: 1: 2: 133-137	전문보기
박경원, 강도영*, 김재우
동아대학교 의과대학 신경과학교실, 핵의학교실
A Case of Idiopathic Normal Pressure Hydrocephalus Showing Marked Improvement of Frontal Lobe Dysfunction
Kyung Won Park, M.D., Do-Young Kang, M.D.*, Jae Woo Kim, M.D.
Department of Neurology, Nuclear Medicine* College of Medicine, Dong-A University, Busan, Korea
Normal pressure hydrocephalus (NPH) is one of the few treatable causes of dementia. The dementia type of NPH is subcortical and characterized by inertia, forgetfulness, and poor executive function. We report a patient with idiopathic NPH who showed marked improvement of frontal executive dysfunction after shunt operation. Brain MRI showed marked enlargement of ventricular system, and neuropsychological tests performed before shunt operation demonstrated cognitive impairment predominantly in frontal-executive and memory functions. Brain perfusion SPECT showed diffusely decreased perfusion in the cerebral cortex and subcortical area. After shunt operation, the diffuse hypoperfusion on SPECT improved, as did frontal-executive and memory functions on neuropsychological tests.
Key Words: Normal pressure hydrocephalus, Frontal lobe dysfunction, Brain perfusion SPECT