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Original Article
Dementia and Neurocognitive Disorders 2012: 11: 4: 146-153

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검사-재검사 간격이 K-MMSE 점수 변화의 유의성 지표에 미치는 영향
송민지·김지향*·유경†·김지현†·이주일‡·강연욱*,‡
한림대학교춘천성심병원 신경과, 한림대학교성심병원 신경과*, 한림대학교 고령사회연구소†, 한림대학교 심리학과‡
The Influence of Test-Retest Interval on the Significant Change Indices for the K-MMSE
Minji Song, M.A., Jihyang Kim, M.A.*, Kyung Ryu, Ph.D.†, Jihyun Kim, Ph.D.†, Juil Rie, Ph.D.‡, Yeonwook Kang, Ph.D.*,‡
Department of Neurology, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon; Department of Neurology*, Hallym University Sacred Heart Hospital, Anyang; Hallym University Institute of Aging†, Chuncheon; Department of Psychology‡, Hallym University, Chuncheon, Korea
Background: The Mini-Mental State Examination (MMSE) has been commonly used to measure cognitive change over time. The aim of present study was to investigate the normative rates of change for the MMSE across test-retest intervals. Methods: We administered the Korean MMSE (K-MMSE) to 1055 community-dwelling middle aged and older adults three times over 6 years. Based on the Christensen’s health screening criteria (1991), 234 middle-aged healthy adults (104 men, 130 women; mean age 55.95 ±6.20 years; age range 45-64 years; mean education 7.63±4.06 years) and 505 healthy elderly (200 men, 305 women; mean age 71.00±4.62 years; age range 65-79 years; mean education 5.61±5.12 years) were selected for the statistical analysis. Reliable change indices were computed using two different statistical methods, the Reliable Change Index adjusted for practice effects (RCIPE; Chelune et al., 1993) and the Standardized Regression-Based Change Index (SRBCI; McSweeny et al., 1993). Results: For the middle-aged healthy adult group, the 90% confidence intervals of the RCIPE and SRBCI were the same such as ±4 in 2-year, ±5 in 4-year, and ±6 in 6-year test-retest intervals. For the healthy elderly group, the 90% confidence intervals of the RCIPE were -5 and +4 in 2-year interval and -7 and +5 in 4- & 6-year intervals. The 90% confidence intervals of the SRB change index were ±4 in 2-year interval and ±6 in 4- & 6-year intervals. Conclusions: The result provides the normative data of the reliable change scores for the K-MMSE for the middle-aged and older adults. It shows that the reliable change indices were varied across different age groups as well as test-retest intervals.
Key Words: MMSE, Test-retest interval, Reliable change index, Standardized regression based change index
대한치매학회지 (Dementia and Neurocognitive Disorders)