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| Original Article | |||||
| Dementia and Neurocognitive Disorders 2011: 10: 3: 95-101 | |||||
| 원본 기호잇기검사와 두 가지 한국판 기호잇기검사의 비교 | |||||
|---|---|---|---|---|---|
| 김현정*, 백민재*, 장영희†, 장일미†, 류희진‡, 김민영‡, 한설희‡, 김상윤§ | |||||
| 분당서울대학교병원 뇌신경센터*, 분당서울대학교병원 신경과†, 건국대학교병원 신경과‡, 분당서울대학교병원 신경과·서울대학교 의과대학 신경과§ | |||||
| Comparison between the Original Version of Trail Making Test with Two Korean-Trail Making Tests | |||||
| Hyun Jung Kim, M.A., Min Jae Baek, M.S., YoungHee Chang, M.D., Il Mi Jang, M.D., Hui Jin Ryu, M.A.†, Minyoung Kim, M.A.†, Seol-Heui Han, M.D.†, SangYun Kim, M.D.* | |||||
| Clinical Neuroscience Center, Seoul National University Bundang Hospital, Department of Neurology*, Seoul National University College of Medicine, Department of Neurology†, Konkuk University Medical Center, Seoul, Korea | |||||
| Background: The Trail Making Test (TMT) is commonly used as a neuropsychological test in clinical practice. However, the B form of original TMT (TMT-OR-B) is limited to use in other countries because it is made up with English alphabets. Therefore, in this study, two versions of Korean TMT (TMT-K: TMT-Korean Letter-B and TMT-Korean Consonant-B) and TMT-OR-B were used to examine the cognitive function for the elderly people in Korea. The purpose of this study was to find which version of three TMT was more sensitive to discriminate the group of patients with cognitive impairment in Korea and to judge whether the TMT-K was necessary. Methods: Total 115 participants (subjective memory impairment: SMI; mild cognitive impairment: MCI; early stage of Alzheimer’s disease: EAD) were tested in two vesrions of TMT-K and the TMT-OR-B. To analyze the sensitivity of these tests, we drew the receiver operating characteristics (ROC) curve and estimated area under the curve (AUC). Results: In the TMT-KL-B, it discriminated significantly between MCI and EAD (AUC=0.863) and SMI and EAD (AUC=0.917). In the TMT-OR-B, the sensitivity is relatively high in distinguishing among three groups (the AUC of SMI and MCI: 0.784; the AUC of MCI and EAD: 0.722; the AUC of SMI and EAD: 0.945). Conclusions: Consequently, the TMT-OR-B is useful for examining cognitive dysfunction of old people in Korea. However, the TMT-OR-B is more appropriate for the high-educated rather than the low-educated to differentiate normal cognitive aging from MCI or EAD. | |||||
| Key Words: Trail Making Test, Mild Cognitive Impairment, Alzheimer’s disease | |||||
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