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경도인지장애와 운동과다증을 동반한 Fahr 환자 1예
Case Report
Dementia and Neurocognitive Disorders 2010: 9: 2: 50-54	전문보기
윤영신∙강희진∙김정은∙김범산*∙박기덕∙최경규∙정지향
이화여자대학교 의과대학 부속목동병원 신경과학교실, 핵의학과*
A Case of Fahr Disease with Mild Cognitive Impairment and Hyperkinesia
Youngshin Yoon, M.D., Hee Jin Kang, M.D., Jung Eun Kim, M.D., Bum Sahn Kim, M.D.*, Kee Duk Park, M.D., Kyoung-Gyu Choi, M.D., Jee H. Jeong, M.D.
Departments of Neurology and Nuclear Medicine*, Cognitive and Neurodegenerative Disorder Clinic, Ewha Womans University Medical Center, Ewha Womans University School of Medicine, Seoul, Korea
A 66-yr-old woman presented with progressive cognitive decline and mild hyperkinetic motor symptoms. Neuropsychological evaluation revealed impairment of memory and frontal executive functions with normal activities of daily living, indicating a mild cognitive impairment. Brain imaging showed extensive calcification involving bilateral basal ganglia, thalamus, occipital cortex and cerebellum consistent with Fahr disease. FDG-PET showed diffuse glucose hypometabolism in bilateral fronto-temporo-parietal cortices, suggesting the disruption of frontal subcortical circuit to be probably associated with the cognitive impairment of the patient.
Key Words: Fahr disease, Mild cognitive impairment, PET