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Case Report
Dementia and Neurocognitive Disorders 2009: 8: 2: 126-130

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헤르페스 뇌염 환자에서 관찰된 35년간의 역행성 기억장애
임성철∙양동원∙홍윤정∙조아현
가톨릭대학교 의과대학 신경과학교실
A Case of Herpes Encephalitis Showing Retrograde Amnesia for the Past 35 Years
Sung-chul Lim, M.D., Dong-won Yang, M.D., Yun Jeong Hong, M.D., A-Hyun Cho, M.D.
Department of Neurology, The Catholic University of Korea, College of Medicine, Seoul, Korea
After damage to the hippocampal memory system, patients tend to lose more of their recent than of their remote memories. This pattern is referred to as the Ribot gradient. One explanation for the gradient of memory loss is consolidation theory of long-term memories. However, the consolidation theory cannot explain the retrograde amnesia for more than 25 yr. We describe here a case of disproportionate retrograde amnesia for the past 35 yr following herpes encephalitis.
Key Words: Retrograde amnesia, Ribot gradient, Consolidation theory