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Original Article
2026; 25 1 - 12
Exploring the Gut-Brain Connection: The Role of Microbiota in Alzheimer’s Disease Pathogenesis

Azar Rahi ,1 Erfaneh Jafari ,2,3 Reza Azizian ,2,3 Mohammad Reza Mohammadi ,4 Atousa Razmfarsa ,5 Sara Shakeri Hosseinabad ,6 Masoud Hamidi 7
1Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 2Pediatric Infectious Diseases Research Center (PIDRC), Tehran University of Medical Sciences, Tehran, Iran 3 Biomedical Innovation and Start-Up Student Association (Biomino), Tehran University of Medical Sciences, Tehran, Iran 4Department of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran 5 Department of Biology and Genetics, Faculty of Science, Islamic Azad University, Mashhad Branch, Razavi Khorasan, Iran 6 Department of Food Microbiology, School of Public Medical Science, Tehran University Medical Science, Tehran, Iran 7 Medical Biotechnology Research Center, School of Paramedicine, Guilan University of Medical Sciences, Rasht, Iran

Exploring the Gut-Brain Connection: The Role of Microbiota in Alzheimer’s Disease Pathogenesis

Azar Rahi ,1 Erfaneh Jafari ,2,3 Reza Azizian ,2,3 Mohammad Reza Mohammadi ,4 Atousa Razmfarsa ,5 Sara Shakeri Hosseinabad ,6 Masoud Hamidi 7
1Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 2Pediatric Infectious Diseases Research Center (PIDRC), Tehran University of Medical Sciences, Tehran, Iran 3 Biomedical Innovation and Start-Up Student Association (Biomino), Tehran University of Medical Sciences, Tehran, Iran 4Department of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran 5 Department of Biology and Genetics, Faculty of Science, Islamic Azad University, Mashhad Branch, Razavi Khorasan, Iran 6 Department of Food Microbiology, School of Public Medical Science, Tehran University Medical Science, Tehran, Iran 7 Medical Biotechnology Research Center, School of Paramedicine, Guilan University of Medical Sciences, Rasht, Iran

2026; 25 1 - 12
Alzheimer’s Disease; Brain-Gut Axis; Microbiota; Probiotics; Prebiotics; Synbiotics;
Original Article
2026; 25 13 - 24
Exploring the Association Between Physical Fitness Components and Cognitive Function in Older Korean Adults: The SUPERBRAIN Exploratory Sub-study

Da Ae Kim ,1 Buongo Chun ,2 Muncheong Choi ,3 Kyunghwa Sun ,1 Jee Hyang Jeong ,4 Yoo Kyoung Park ,5 Chang Hyung Hong ,6 Hae Ri Na ,7 Seong Hye Choi ,8 So Young Moon ,1 Hong-sun Song ,9,* Sun Min Lee 1,*
1Department of Neurology, Ajou University School of Medicine, Suwon, Korea 2Graduate School of Physical Education, Myungji University, Yongin, Korea 3Exercowork, Hanam, Korea 4 Department of Neurology, Ewha Womans University Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Korea 5 Department of Medical Nutrition, Graduate School of East-West Medical Nutrition, Kyung Hee University, Suwon, Korea 6Department of Psychiatry, Ajou University School of Medicine, Suwon, Korea 7Department of Neurology, Bobath Memorial Hospital, Seongnam, Korea 8Department of Neurology, Inha University College of Medicine, Incheon, Korea 9Department of Physical Education, Gyeongkuk National University, Andong, Korea

Exploring the Association Between Physical Fitness Components and Cognitive Function in Older Korean Adults: The SUPERBRAIN Exploratory Sub-study

Da Ae Kim ,1 Buongo Chun ,2 Muncheong Choi ,3 Kyunghwa Sun ,1 Jee Hyang Jeong ,4 Yoo Kyoung Park ,5 Chang Hyung Hong ,6 Hae Ri Na ,7 Seong Hye Choi ,8 So Young Moon ,1 Hong-sun Song ,9,* Sun Min Lee 1,*
1Department of Neurology, Ajou University School of Medicine, Suwon, Korea 2Graduate School of Physical Education, Myungji University, Yongin, Korea 3Exercowork, Hanam, Korea 4 Department of Neurology, Ewha Womans University Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Korea 5 Department of Medical Nutrition, Graduate School of East-West Medical Nutrition, Kyung Hee University, Suwon, Korea 6Department of Psychiatry, Ajou University School of Medicine, Suwon, Korea 7Department of Neurology, Bobath Memorial Hospital, Seongnam, Korea 8Department of Neurology, Inha University College of Medicine, Incheon, Korea 9Department of Physical Education, Gyeongkuk National University, Andong, Korea

2026; 25 13 - 24
Dementia; Cognition; Physical Fitness; Physical Exercise; Aging; Prevention;
Original Article
2026; 25 25 - 41
A Protocol of Korean JOint RegistrY for ALZheimer’s Treatment and Diagnostics (JOY-ALZ)

Geon Ha Kim ,1,* Jung-Min Pyun ,2,* Danbee Kang ,3,* Sung Hoon Kang ,4 Seong-Ho Koh ,5 Jae Seung Kim ,6 So Young Moon ,7 Won-Jin Moon ,8 Young Ho Park ,2 YongSoo Shim ,9 Dong Won Yang ,10 Young Chul Youn ,11 Young Hee Jung ,12 Hanna Cho ,13 Hojin Choi ,5 Jae-Sung Lim ,14 Kee Hyung Park ,15 Seong Hye Choi 16
1 Department of Neurology, Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, Korea 2 Department of Neurology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea 3Department of Clinical Research Design and Evaluation, SAIHST, Sungkyunkwan University, Seoul, Korea 4 Department of Neurology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea 5 Department of Neurology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea 6 Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea 7Department of Neurology, Ajou University Hospital, Ajou University School of Medicine, Suwon, Korea 8 Department of Radiology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea 9 Department of Neurology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea 10 Department of Neurology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea 11Department of Neurology, Chung-Ang University College of Medicine, Seoul, Korea 12 Department of Neurology, Hallym Sacred Heart Hospital, College of Medicine, Hallym University, Anyang, Korea 13 Department of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea 14Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea 15 Department of Neurology, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Korea 16Department of Neurology, Inha University College of Medicine, Incheon, Korea

A Protocol of Korean JOint RegistrY for ALZheimer’s Treatment and Diagnostics (JOY-ALZ)

Geon Ha Kim ,1,* Jung-Min Pyun ,2,* Danbee Kang ,3,* Sung Hoon Kang ,4 Seong-Ho Koh ,5 Jae Seung Kim ,6 So Young Moon ,7 Won-Jin Moon ,8 Young Ho Park ,2 YongSoo Shim ,9 Dong Won Yang ,10 Young Chul Youn ,11 Young Hee Jung ,12 Hanna Cho ,13 Hojin Choi ,5 Jae-Sung Lim ,14 Kee Hyung Park ,15 Seong Hye Choi 16
1 Department of Neurology, Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, Korea 2 Department of Neurology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea 3Department of Clinical Research Design and Evaluation, SAIHST, Sungkyunkwan University, Seoul, Korea 4 Department of Neurology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea 5 Department of Neurology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea 6 Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea 7Department of Neurology, Ajou University Hospital, Ajou University School of Medicine, Suwon, Korea 8 Department of Radiology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea 9 Department of Neurology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea 10 Department of Neurology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea 11Department of Neurology, Chung-Ang University College of Medicine, Seoul, Korea 12 Department of Neurology, Hallym Sacred Heart Hospital, College of Medicine, Hallym University, Anyang, Korea 13 Department of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea 14Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea 15 Department of Neurology, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Korea 16Department of Neurology, Inha University College of Medicine, Incheon, Korea

2026; 25 25 - 41
Alzheimer Disease; Treatment; Monoclonal Antibody; Diagnosis; Biomarkers; Dataset;
Original Article
2026; 25 42 - 53
The Clinical Utility of the Cognitive Impairment Screening Test (CIST)

Hyeseon Han ,1 ,* Soyeon Lim ,1,* Suah Kim ,1 Byung Hwa Lee ,1 Hee Jin Kim ,1,2 Juhee Chin 1,3,4,5
1 Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea 2Neuroscience Center, Samsung Medical Center, Seoul, Korea 3Department of Psychology, Hallym University, Chuncheon, Korea 4Research Institute of Humanities & Social Science Convergence, Hallym University, Chuncheon, Korea 5Hallym Institute for Applied Psychological Research, Hallym University, Chuncheon, Korea

The Clinical Utility of the Cognitive Impairment Screening Test (CIST)

Hyeseon Han ,1 ,* Soyeon Lim ,1,* Suah Kim ,1 Byung Hwa Lee ,1 Hee Jin Kim ,1,2 Juhee Chin 1,3,4,5
1 Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea 2Neuroscience Center, Samsung Medical Center, Seoul, Korea 3Department of Psychology, Hallym University, Chuncheon, Korea 4Research Institute of Humanities & Social Science Convergence, Hallym University, Chuncheon, Korea 5Hallym Institute for Applied Psychological Research, Hallym University, Chuncheon, Korea

2026; 25 42 - 53
Cognitive Screening Test; Mild Cognitive Impairment; Dementia; Amyloid-Beta; CIST; SNSB-II;
Original Article
2026; 25 54 - 68
Effects of Prior Exercise Habits and Adherence on Cognitive Function, Physical Fitness, and Vascular Health in Older Adults: An Exploratory Exercise-Based Intervention Trial

Da Ae Kim ,1 Muncheong Choi ,2 Buongo Chun ,3 Kyunghwa Sun ,1 So Young Moon ,1 Hong-Sun Song ,4 Sun Min Lee 1
1Department of Neurology, Ajou University School of Medicine, Suwon, Korea 2Exercowork, Hanam, Korea 3Graduate School of Physical Education, Myungji University, Yongin, Korea 4Department of Physical Education, Gyeongkuk National University, Andong, Korea

Effects of Prior Exercise Habits and Adherence on Cognitive Function, Physical Fitness, and Vascular Health in Older Adults: An Exploratory Exercise-Based Intervention Trial

Da Ae Kim ,1 Muncheong Choi ,2 Buongo Chun ,3 Kyunghwa Sun ,1 So Young Moon ,1 Hong-Sun Song ,4 Sun Min Lee 1
1Department of Neurology, Ajou University School of Medicine, Suwon, Korea 2Exercowork, Hanam, Korea 3Graduate School of Physical Education, Myungji University, Yongin, Korea 4Department of Physical Education, Gyeongkuk National University, Andong, Korea

2026; 25 54 - 68
Elderly; Physical Fitness; Cognitive Function; Physical Exercise; Dementia;
Original Article
2026; 25 69 - 78
Concordance Between Subtest-Based and Domain Score-Based Determinations of Cognitive Impairment on the SNSB-II

Yeje Ban ,1 Hyun Ho Lee ,2 Jae-Sung Lim ,3 Yeonwook Kang 4
1Department of Neurology, Kyung Hee University Hospital, Seoul, Korea 2Department of Neurology, Yongin Severance Hospital, Yongin, Korea 3Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea 4Department of Psychology, Hallym University, Chuncheon, Korea

Concordance Between Subtest-Based and Domain Score-Based Determinations of Cognitive Impairment on the SNSB-II

Yeje Ban ,1 Hyun Ho Lee ,2 Jae-Sung Lim ,3 Yeonwook Kang 4
1Department of Neurology, Kyung Hee University Hospital, Seoul, Korea 2Department of Neurology, Yongin Severance Hospital, Yongin, Korea 3Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea 4Department of Psychology, Hallym University, Chuncheon, Korea

2026; 25 69 - 78
Seoul Neuropsychological Screening Battery, Second Edition (SNSB-II); Subtest Score; Cognitive Domain Score; Cognition;
Original Article
2026; 25 79 - 89
Predicting Brain Amyloid PET Positivity Using the Amyloid Beta Composite (ABC) Index in Patients With Cognitive Impairment

Juyoun Lee ,1,* Sukyoung Jung ,2,3,* Ae Young Lee 1
1 Department of Neurology, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea 2 Department of Health Care Policy Research, Korea Institute for Health and Social Affairs, Sejong, Korea 3Biomedical Research Institute, Chungnam National University Hospital, Daejeon, Korea

Predicting Brain Amyloid PET Positivity Using the Amyloid Beta Composite (ABC) Index in Patients With Cognitive Impairment

Juyoun Lee ,1,* Sukyoung Jung ,2,3,* Ae Young Lee 1
1 Department of Neurology, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea 2 Department of Health Care Policy Research, Korea Institute for Health and Social Affairs, Sejong, Korea 3Biomedical Research Institute, Chungnam National University Hospital, Daejeon, Korea

2026; 25 79 - 89
Alzheimer Disease; Mild Cognitive Impairment; Positron Emission Tomography; Amyloid Beta-Peptides; Models, Statistical;
Original Article
2026; 25 90 - 90
Erratum: Nationwide Survey on the Awareness of Mild Cognitive Impairment

Hyuk Sung Kwon ,1 Kee Hyung Park ,2 Jin San Lee ,3 Hojin Choi ,1 Chan-Nyoung Lee ,4 Jae-Sung Lim ,5 Jae-Won Jang ,6 YongSoo Shim ,7 Seong Hye Choi ,8 Dong Won Yang 9
1 Department of Neurology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea 2 Department of Neurology, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Korea 3 Department of Neurology, Kyung Hee University Hospital, Kyung Hee University College of Medicine, Seoul, Korea 4 Department of Neurology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea 5Department of Neurology, Asan Medical Center, Seoul, Korea 6 Department of Neurology, Kangwon National University Hospital, Kangwon National University College of Medicine, Chuncheon, Korea 7 Department of Neurology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea 8Department of Neurology, Inha University Hospital, Inha University College of Medicine, Incheon, Korea 9 Department of Neurology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea

Erratum: Nationwide Survey on the Awareness of Mild Cognitive Impairment

Hyuk Sung Kwon ,1 Kee Hyung Park ,2 Jin San Lee ,3 Hojin Choi ,1 Chan-Nyoung Lee ,4 Jae-Sung Lim ,5 Jae-Won Jang ,6 YongSoo Shim ,7 Seong Hye Choi ,8 Dong Won Yang 9
1 Department of Neurology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea 2 Department of Neurology, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Korea 3 Department of Neurology, Kyung Hee University Hospital, Kyung Hee University College of Medicine, Seoul, Korea 4 Department of Neurology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea 5Department of Neurology, Asan Medical Center, Seoul, Korea 6 Department of Neurology, Kangwon National University Hospital, Kangwon National University College of Medicine, Chuncheon, Korea 7 Department of Neurology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea 8Department of Neurology, Inha University Hospital, Inha University College of Medicine, Incheon, Korea 9 Department of Neurology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea

2026; 25 90 - 90
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